Channel 4 is marking 10 years of fundraising for its Stand Up to Cancer (SU2C) campaign with a dedicated night of comedy programming.

SU2C: The Takeover will broadcast live at 7pm on 3 November from the Francis Crick Institute and will be hosted by Davina McCall, Adam Hills, Joe Lycett and Munya Chawawa.

The 90-minute live show will feature entertainment and comedy talent, such as Oti Mabuse, Cush Jumbo and Ghosts stars Kiell Smith-Bynoe and Charlotte Ritchie.It will celebrate the breakthroughs in cancer research that have been funded by money raised through SU2C.

The special programming will continue with The SU2C Comedy Roast, hosted by Rhod Gilbert and featuring a roster of comedic talent, including Ellie Taylor, Nish Kumar and Danny Beard, while comedians Sarra Barron, Thaniya Moore, Bobby Mair, Harriet Kemsley, Fatiha El-Ghorri and Larry Dean will take part in a ‘roast roulette’ in aid of SU2C.

Also scheduled is a new episode of Studio Lambert’s Celebrity Gogglebox and the finale of South Shore’s Don’t Look Down, which will see Paddy McGuinness lead his team of celebrities as they attempt a world-first relay highwire walk over the London Stadium.

The night will end with Sean Lock: Lockipedia, in memory of one of C4’s best-known comic faces. Lock died from lung cancer in 2021 at the age of 58.

SU2C: The Takeover and The SU2C Comedy Roast are both produced by Monkey and were commissioned for C4 by Tom Beck, head of live events, with Phil Harris, the outgoing head of entertainment, and Antonia Howard-Taylor, commissioning executive. They will be exec produced for Monkey by Andy Charles Smith and Suzi Aplin.

In the lead-up to the night of celebrations, C4 will air documentary Rhod Gilbert: A Pain in the Neck, produced by Welsh indie Kailash Films.

Comedian Gilbert has raised over £2m for cancer care over the span of a decade and it was on a fundraising trek for Cardiff’s Velindre Cancer Hospital that he noticed worrying symptoms that would lead to a diagnosis of head and neck cancer.

The doc is told through Gilbert’s own personal video diaries, with his characteristic unflinching and mordant humour, the comedian will detail his experience of living with cancer and his treatment at the hospital he has supported for a decade.

The Stand Up to Cancer campaign is run in partnership with Cancer Research UK and has raised £93m since it began in 2013. The money has funded 64 clinical trials and research projects, involving over 13,000 patients, and has led to breakthroughs in treatment, including kinder testing for breast cancer to a new treatment for advanced bile duct cancer.

C4’s Stand Up to Cancer night airs from 7pm on Friday 3 November